Chemotherapy is a common treatment option for mesothelioma, a type of cancer that affects the lining of the chest or abdomen, often caused by exposure to asbestos. Several chemotherapy drugs are used either alone or in combination to target and kill cancer cells or slow their growth. Some of the chemotherapy drugs commonly used for mesothelioma include:
Cisplatin
This drug is frequently used in combination with other chemotherapy agents. It works by damaging the DNA of cancer cells, preventing them from multiplying.
Carboplatin
Similar to cisplatin, carboplatin also disrupts the growth of cancer cells by damaging their DNA. It may be used if a patient cannot tolerate cisplatin.
Pemetrexed (Alimta)
Often used in combination with cisplatin, pemetrexed is a chemotherapy drug that interferes with the production of DNA and RNA, thus slowing down the growth of cancer cells.
Gemcitabine
This drug works by interfering with the process of DNA replication in cancer cells, ultimately leading to their death.
Vinorelbine
It’s another chemotherapy drug that disrupts the cancer cells’ ability to divide and grow.
These drugs may be administered in different ways, including intravenously (IV), orally in pill form, or directly into the affected area in some cases.
It’s important to note that while chemotherapy can be effective in treating mesothelioma by shrinking tumors and alleviating symptoms, it often comes with side effects such as nausea, fatigue, hair loss, and a weakened immune system. Treatment plans and drug choices may vary depending on the stage of the cancer, the patient’s overall health, and other individual factors. Combination therapies, including chemotherapy along with surgery or radiation therapy, might also be recommended by oncologists to improve outcomes. Always consult with a medical professional for personalized information and treatment options.