Chemotherapy

HITHOC for Pleural Mesothelioma

HITHOC stands for Hyperthermic IntraThoracic Chemotherapy. It’s a form of treatment used for certain types of cancers that affect the lining of the chest cavity, such as pleural mesothelioma. Pleural mesothelioma is a cancer caused by exposure to asbestos and primarily affects the lining of the lungs (pleura).

HITHOC involves two primary components: cytoreductive surgery and hyperthermic intrathoracic chemotherapy.

Cytoreductive Surgery

This is a major surgical procedure aimed at removing visible tumors and cancerous tissues within the chest cavity. The goal is to reduce the tumor burden as much as possible.

Hyperthermic Intrathoracic Chemotherap

After the surgery, while the chest cavity is still open, a heated chemotherapy solution is circulated throughout the chest for a period of time. The high temperature helps enhance the effectiveness of the chemotherapy drugs and can better penetrate the remaining cancer cells, potentially improving outcomes.

HITHOC is considered in cases where the cancer is confined to the chest cavity and has not spread extensively beyond that area. It aims to improve the effectiveness of treatment by delivering chemotherapy directly to the affected area at an elevated temperature, potentially increasing the drugs’ ability to kill cancer cells.

However, it’s essential to note that not all patients with pleural mesothelioma are suitable candidates for HITHOC. The eligibility for this treatment depends on various factors, including the stage of cancer, the patient’s overall health, and the extent of tumor spread.

As with any treatment, HITHOC also carries risks and potential side effects, including those associated with major surgery and chemotherapy. Patients considering this option should discuss its potential benefits and risks thoroughly with their healthcare team to make an informed decision.

Treatment approaches for mesothelioma, including HITHOC, may vary based on individual cases and advancements in medical research. Always consult with qualified healthcare professionals for the most accurate and up-to-date information on treatment options for pleural mesothelioma.

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