Types

What Is the Treatment for Peritoneal Mesothelioma?

The treatment for peritoneal mesothelioma, a rare and aggressive cancer that affects the lining of the abdomen (peritoneum), typically involves a combination of therapies. The choice of treatment depends on various factors, including the stage of the cancer, the patient’s overall health, and individual preferences. Treatment options for peritoneal mesothelioma may include:

  1. Surgery:
    • Cytoreductive surgery (CRS): This is a major surgical procedure aimed at removing as much of the tumor as possible. During CRS, the surgeon may also remove affected organs or tissues within the abdominal cavity.
    • Hyperthermic intraperitoneal chemotherapy (HIPEC): After CRS, HIPEC is often administered. Heated chemotherapy drugs are circulated within the abdominal cavity to kill any remaining cancer cells.
  2. Chemotherapy:
    • Systemic chemotherapy: Chemotherapy drugs can be given orally or intravenously to target cancer cells throughout the body.
    • Intraperitoneal chemotherapy: Chemotherapy drugs can be administered directly into the abdominal cavity to increase their concentration in the area affected by mesothelioma.
  3. Radiation therapy:
    • Radiation therapy may be used to shrink tumors or relieve symptoms, although it is less commonly used for peritoneal mesothelioma compared to other treatment modalities.
  4. Targeted therapy:
    • Emerging treatments such as targeted therapies and immunotherapy may be considered in clinical trials. These therapies aim to specifically target cancer cells while minimizing damage to healthy cells.
  5. Supportive care:
    • Palliative care may be incorporated to manage pain, discomfort, and other symptoms associated with peritoneal mesothelioma and its treatment.
  6. Clinical trials:
    • Participation in clinical trials can provide access to experimental treatments and therapies that may offer potential benefits.

It’s important for individuals diagnosed with peritoneal mesothelioma to consult with a multidisciplinary team of healthcare professionals, including oncologists, surgeons, and radiologists, to determine the most appropriate treatment plan. The choice of treatment will depend on the specific characteristics of the cancer and the patient’s overall health. Additionally, treatment plans may be personalized to optimize outcomes and quality of life.

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