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What Causes Peritoneal Mesothelioma?

What Causes Peritoneal Mesothelioma?

Peritoneal mesothelioma is a rare and aggressive cancer that affects the lining of the abdomen, known as the peritoneum. This type of cancer is primarily caused by exposure to asbestos, a naturally occurring mineral that was once widely used in various industries for its heat-resistant and insulating properties. When asbestos fibers are inhaled or ingested, they can become trapped in the body, leading to various health problems, including mesothelioma.

Here are the key factors that contribute to the development of peritoneal mesothelioma:

  1. Asbestos Exposure: The primary risk factor for peritoneal mesothelioma is exposure to asbestos. People who have worked in industries such as construction, shipbuilding, automotive manufacturing, and asbestos mining are at a higher risk of inhaling or ingesting asbestos fibers during their careers. Even indirect exposure, such as washing the clothes of someone who worked with asbestos, can pose a risk.
  2. Duration of Exposure: The risk of developing peritoneal mesothelioma is often associated with the duration and intensity of asbestos exposure. Long-term, heavy exposure increases the likelihood of developing the disease.
  3. Type of Asbestos: There are different types of asbestos fibers, with amphibole asbestos (including crocidolite and amosite) being more strongly associated with mesothelioma compared to chrysotile asbestos. However, all types of asbestos have been linked to the disease.
  4. Genetic Factors: Some research suggests that genetic factors may play a role in an individual’s susceptibility to asbestos-related diseases, including peritoneal mesothelioma. However, asbestos exposure remains the primary factor.

It’s important to note that peritoneal mesothelioma has a long latency period, meaning that symptoms may not appear until many years (typically 20-50 years) after the initial asbestos exposure. Common symptoms of peritoneal mesothelioma include abdominal pain, swelling, fluid accumulation in the abdomen (ascites), weight loss, and digestive problems.

If you suspect you may have been exposed to asbestos and are experiencing symptoms, it is essential to seek medical attention promptly. Early diagnosis and treatment can significantly improve the prognosis for peritoneal mesothelioma. Treatment options typically include surgery, chemotherapy, and radiation therapy, depending on the stage and extent of the disease.