Pleural mesothelioma is a rare and aggressive form of cancer that affects the tissue that lines the lungs and chest. It is caused by exposure to asbestos, a mineral fiber that was widely used in building materials and products prior to the 1980s. Asbestos exposure can lead to a number of health issues, including pleural mesothelioma.
The exact mechanism of how asbestos causes pleural mesothelioma is not yet fully understood. However, researchers have identified a number of potential causes that can lead to the development of this cancer. These include:
1. Long-term, high- level exposure to asbestos: Asbestos fibers can be inhaled or ingested over an extended period of time, leading to chronic inflammation and irritation of the mesothelial tissue. This inflammation can cause genetic damage that leads to the development of pleural mesothelioma.
2. Genetic mutations: Certain mutations in the BAP1 gene have been linked to a higher risk of developing pleural mesothelioma.
3. Radon exposure: Radon is a naturally occurring radioactive gas that is released from rocks and soils. High levels of radon can increase the risk of developing pleural mesothelioma.
4. Smoking: Smoking is known to increase the risk of developing pleural mesothelioma, especially in individuals who have been exposed to asbestos.
5. Environmental toxins: There are environmental toxins, such as benzene, that can increase the risk of developing pleural mesothelioma.
These potential causes can help researchers better understand the development of this disease in order to find more effective treatments. It is important to note that while these potential causes may increase the risk of developing pleural mesothelioma, the only known cause of this cancer is exposure to asbestos. Therefore, it is important to take steps to reduce your risk of asbestos exposure.
It is also important to remember that pleural mesothelioma is a rare and aggressive form of cancer. If you have been exposed to asbestos, it is important to speak to your doctor about your risk of developing this disease.
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